Tanzania – Sanaria

Sanaria and its Bioko Island Malaria Elimination Project partners win the Concordia P3 Impact Award and Audience Choice Award

September 24, 2019 By Alexander Hoffman In Awards, In The Media, News No Comments

The Bioko Island Malaria Elimination Project (BIMEP) is a long-term partnership dedicated since 2004 to the elimination of malaria from Equatorial Guinea which had one of the highest rates of malaria transmission and where the disease was the leading cause of morbidity and mortality.

Safety and Differential Antibody and T-Cell Responses to the Plasmodium falciparum Sporozoite Malaria Vaccine, PfSPZ Vaccine, by Age in Tanzanian Adults, Adolescents, Children, and Infants

June 1, 2019 By Alexander Hoffman In Publications No Comments

Abstract

In 2016, there were more cases and deaths caused by malaria globally than in 2015. An effective vaccine would be an ideal additional tool for reducing malaria’s impact. Sanaria® PfSPZ Vaccine, composed of radiation-attenuated, aseptic, purified, cryopreserved Plasmodium falciparum (Pf) sporozoites (SPZ) has been well tolerated and safe in malaria- na ̈ıve and experienced adults in the United States and Mali and protective against controlled human malaria infection with Pf in the United States and field transmission of Pf in Mali, but had not been assessed in younger age groups. We, therefore, evaluated PfSPZ Vaccine in 93 Tanzanians aged 45 years to 6 months |